21/06/2021 - Press release
As a result of the collaboration between research centres in Italy and Spain, the PEGASUS study has been launched with the aim of demonstrating that, thanks to the liquid biopsy guidance tool, it is possible to increase the precision of post-surgical treatment for colon cancer patients. The Vall d'Hebron Institute of Oncology (VHIO), part of the Vall d'Hebron Campus, and the Hospital del Mar Medical Research Institute (IMIM), both in Barcelona; and the INCLIVA Health Research Institute at Hospital Clínico in Valencia, are the three Spanish centres taking part in this project. The study was instigated by Dr. Silvia Marsoni, from the FIRC Institute of Molecular Oncology (IFOM) in Milan, and is supported by the AIRC Foundation within the 5x1000 programme, which is coordinated by Prof. Alberto Bardelli of the University of Turin and the Institute of Candiolo FPO-IRCCS.
19/05/2021 - Press release
Liquid biopsy can predict which patients with localised rectal cancer are likely to relapse, even after initial chemotherapy and radiotherapy treatment, and prior to surgery. This is supported by a study led by doctors and researchers from the Medical Oncology and Pathology Departments at Hospital del Mar, as well as the Hospital de Mar Medical Research Institute (IMIM) and the CIBER in cancer (CIBERONC), which has been published in the American Association for Cancer Research journal, Clinical Cancer Research. The study analysed samples from 72 patients from twenty hospitals in Spain, taken as part of the GEMCAD1402 clinical trial conducted by the Spanish Multidisciplinary Group on Digestive Cancer.
Més informació "Liquid biopsy can predict relapse in patients with locally advanced rectal cancer"
17/05/2021 - General information
The head of the Medical Oncology Service and director of the Cancer Research Programme at the Hospital del Mar Medical Research Institute is one of the most outstanding specialists among Catalan oncologists. The Governance and Economics Coordinates Institute has just published its TOP 100 ranking of the best doctors working in Catalan hospitals, both public and private. Dr. Joan Albanell, head of the Medical Oncology Department at Hospital del Mar, features among the top ten specialists in the oncology section.
13/05/2021 - Press release
Hospital del Mar-IMIM is leading an international clinical trial to evaluate the performance and suitability of new equipment for locating the sentinel lymph node in prostate cancer patients. The new tool is a flexible, miniaturized probe, which should improve the detection of a marker (a radioactive molecule) injected into the patient to locate the first node the tumour drains to. The technology SENSEI®, has been developed by the UK company Lightpoint Medical with the support of the Hospital del Mar Urology Service.
12/05/2021 - General information
Montagut has been invited to be part of the group of experts who will draft the European Society of Medical Oncology recommendations on the appropriate use of this technique and its implementation in clinical practice. The head of the Digestive Oncology section in the Medical Oncology Service at Hospital del Mar and researcher at the Hospital del Mar Medical Research Institute (IMIM), Dr. Clara Montagut, will be a co-author of the ESMO recommendations for the use of liquid biopsy in cancer patients. The project is led by Professor Nicholas Turner, from the Institute of Cancer Research in London. The initiative is one of the tasks of the organisation's Translational Research and Precision Medicine Working Group.
29/04/2021 - General information
The benchmark meeting in the field of immunotherapy cancer treatment was held once again, on April 9, in a hybrid format. This year, the presentations focused on the research and development of this type of treatment for various types of tumours, as well as molecular diagnostics. Understanding which factors make immunotherapy work in some cancer patients and not in others, the structure and genetics of tumours to help select the most appropriate treatment, is the current focus of research in this field. This was evident at the new edition of the Optimizing Immunotherapy, New Approaches, Biomarkers, Sequences and Combinations congress, held on 9 April in a hybrid format and organised by the Hospital del Mar Medical Research Institute (IMIM) and Hospital del Mar. The meeting brought together around twenty of the world's leading experts in research and clinical application of immunotherapy treatments to analyse the latest breakthroughs and the future of immunotherapy. It was backed by the SEOM, SOGUC and CIBERONC.
Més informació "The future of immunotherapy at the Optimizing Immunotherapy Congress"
22/04/2021 - General information
Dr. Anna Bigas, coordinator of the Stem cells and cancer Research Group of the Hospital del Mar Medical Research Institute (IMIM) and scientific director of the CIBER Oncology has been chosen one of the Top 100 Women Leaders in Spain. This is a ranking created by Mujeres & Cia in 2011, an online magazine of reference among professional women that aims to make female talent visible and build a society based on equality. On the afternoon of April 21, the Top 100 Gala was held, this year in hybrid format, which was attended by Nadia Calviño, Second Vice President of the Government, soprano Pilar Navarro and TV presenter Sonsoles Onega. At the event, the chosen ones were announced, including Dr. Anna Bigas in the category of Academics, researchers and thinkers. Of the 100 chosen, 50 are chosen by a jury, 40 by Mujeres & Cia and 10 by the public through voting.
Més informació "Anna Bigas, one of the Top 100 Women Leaders in Spain"
13/04/2021 - General information
The head of the Digestive Oncology section in the Medical Oncology Service at Hospital del Mar is taking on this new role in the ESMO Faculty until 2025. From now on, she will be part of the group of experts who collaborate with the organisation to fulfil its educational responsibilities. Dr. Clara Montagut is now a member of the ESMO Faculty, the teaching body of the European Society of Medical Oncology, specifically in the gastrointestinal, colon and rectal tumours group. The head of Digestive Oncology at Hospital del Mar and the clinical and translational research group laboratory for new therapies and biomarkers in colon and rectal cancer at the Hospital del Mar Medical Research Institute (IMIM), will form part of the group of experts from the organisation who offer advice and support to help the society fulfil its educational responsibilities.
09/02/2021 - General information
Dr. Bigas has joined as Deputy Director of Preclinical Research at the Josep Carreras Institute, maintaining her relationship with the Hospital del Mar Medical Research Institute (IMIM), where she leads the Stem Cells and Cancer group. The new responsibility that Dr. Bigas assumes will serve to enhance coordination between all groups in the institute that do basic and translational research, seeking synergies between them and optimizing their research, as well as to enhance the existing collaboration between the professionals of our institute and those of the IMIM. In the last ten years, as head of the Stem Cells and Cancer group, she has studied the molecular and physiological processes of stem cells in different tissues, in order to draw similarities with the appearance and progression of cancerous processes. In particular, her research focuses on the study of hematopoietic stem cells, responsible for the formation of blood cells, in order to understand the process of leukemia and develop strategies to fight against this disease.Currently, her research group is working on the identification of epigenetic and gene expression profiles, which allow discovering new therapeutic targets not yet exploited clinically.
20/01/2021 - General information
The Journal of Clinical Investigation has published a review authored by Michelle von Locquenghien, Catalina Rozalén, and Toni Celià-Terrassa, all members of the Cancer Stem Cells & Metastasis Dynamics Lab at the Hospital del Mar Medical Research Institute (IMIM). In the article, they analyse current knowledge on the role of interferons -cytokines (proteins) involved in regulating the function of immune system cells- in the mechanisms that allow tumour cells to develop treatment resistance. The authors explain how the relationship between tumour cells and the immune system evolves as the cancer progresses, causing these cells to acquire systems that enable them to resist attack. They point out that the principal mechanisms used to achieve this are related to interferon signalling. In this respect, they highlight new evidence supporting immunotherapy-mediated immunoediting and show how interferons can impact either treatment response or resistance. All these factors lead the authors to support its potential as a therapeutic strategy in cancer.
Més informació "The role of interferons in tumour cell resistance to immunotherapy"
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