The Critical Illness Research Group (GREPAC) aims at contributing to elucidate the mechanism involved in the onset and progression of different illnesses that cause a reversible dysfunction to one or more organs placing the patient’s life at risk. To do this, our research includes clinical research on patients, and also experimental models. These models allow us to study the molecular mechanisms involved in these processes and to identify therapeutic targets and new strategies against these illnesses and, whenever possible, to anticipate ourselves to these cascades to avoid more illnesses and multi-organ dysfunction.
The critical illness research group conceived Intensive Medicine research from a translational, clinical and multi-disciplinary approach; hence, another important objective is to further study new strategies and treatments by conducting controlled clinical trials and observational projects with a high interest, participating at all possible levels of commitment: as promoters, lead researchers, collaborators in multi-centre projects and developing our own projects.
Main research lines
1. Inflammatory Lung disease. Acute Respiratory Distress Syndrome (ARDS)
2. Studies on biomarkers in other critical patients:
3. Control and prevention of nosocomial infection in critical patients:
4. Optimization of antibiotic treatment:
5. Hemodynamic monitoring:
6. Micro-circulatory alterations in sepsis:
7. Phase II and III clinical trials